Oligonucleotide Synthesis Market

Global Oligonucleotide Synthesis Market Size, Trends & Analysis - Forecasts to 2029 By Application Type (Research, Diagnostics, and Therapeutics), By Product Type (Oligonucleotide-based Drugs, Synthesized Oligonucleotides, Reagents, and Equipment), By End User (Hospitals, Pharmaceutical Companies, Diagnostic Laboratories, and Others), and By Region (North America, Asia Pacific, Central and South America, Europe, and Middle East and Africa), Competitive Landscape, Company Market Share Analysis, and End User Analysis

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This report was recently updated on April 23 2024 with the latest and most recent market numbers

Global Oligonucleotide Synthesis Market Size

The global oligonucleotide synthesis market is expected to exhibit a CAGR of 16.4% from 2024 to 2029. Oligonucleotide synthesis is a chemical combination technique for short fragments of nucleic acids to create a new chemical sequence. Examples of this include DNA and RNA synthesis. This technique has a clear superiority over traditional enzyme combination techniques. Oligonucleotide synthesis does not have the limitation of combining nucleic acids in only the 5’ to 3’ direction. The method is often used in the opposite direction, in the 3’ to 5’ direction.

Many factors drive the growth of the global oligonucleotide synthesis market. One of the most important factors for the popularization of oligonucleotide synthesis techniques on a global scale is the rising prevalence of chronic diseases like spinal muscular atrophy (SMA), amyotrophic lateral sclerosis (ALS), spinocerebellar ataxias, and asthma. These diseases demand the usage of oligonucleotide therapeutics, which increases the demand for oligonucleotide synthesis, driving market growth. Additionally, oligonucleotide synthesis can be used in molecular diagnosis. Oligonucleotides can detect various types of genetic disorders by detecting specific gene mutations in a patient and diagnosis for specific diseases. They are also used in primers in techniques such as polymerase chain reaction (PCR) and reverse transcription polymerase chain reaction (RT-PCR).

Despite the promising growth prospects, the global oligonucleotide synthesis market faces certain restraints that hinder its growth. The synthesis of oligonucleotides is associated with the high cost of production due to various reasons. The chemical reagents and equipment used for the process have a high price. Also, the different post-synthesis processes, like purification, are complicated and result in extensive usage of various equipment, resulting in a higher cost. Another reason for the high cost of production is the scale of synthesis. Usually, the yield of each synthesis is small, and scaling up the yield is an expensive process. All these factors contribute to the high cost of oligonucleotide synthesis.

global oligonucleotide synthesis market

Global Oligonucleotide Synthesis Market: By Application Type

Based on the application type, the market is segmented into research, diagnostics, and therapeutics. The therapeutics segment is expected to be the largest segment during the forecast period. Oligonucleotides are frequently used as therapeutics for the treatment of various diseases. These diseases can be neurological, like spinal muscular atrophy (SMA), amyotrophic lateral sclerosis (ALS), spinocerebellar ataxias, respiratory, like asthma, COPD, and diabetic retinopathy, and various types of cancer. This causes the therapeutics segment to dominate the market.

The research segment is expected to be the fastest-growing segment in the global oligonucleotide synthesis market during the forecast period. The use of oligonucleotide synthesis is crucial in various advanced techniques, such as PCR and next-generation sequencing, catering to the increasing need for genetic analysis and gene sequencing in research. Moreover, the ever-expanding field of drug development and discovery heavily relies on oligonucleotides for the creation of therapeutic nucleic acids. With continuous advancements in synthesis technologies, such as high throughput synthesizers and advanced coupling reagents, nucleic acid chemistry has undergone a significant transformation, resulting in enhanced efficiency and scalability. These factors have led to the impressive development of the research application segment in the oligonucleotide synthesis market.

Global Oligonucleotide Synthesis Market: By Product Type

On the basis of product type, the market is segmented into oligonucleotide-based drugs, synthesized oligonucleotides, reagents, and equipment. The reagent segment is expected to be the largest and fastest-growing segment during the forecast period. Oligonucleotide synthesis heavily relies on specialized chemical reagents, specifically phosphoramidites with protecting groups. These critical components are essential for constructing DNA and RNA sequences with precision and control. The success of the synthesis highly depends on the quality and purity of these reagents, making them an integral factor. With the increasing demand for oligonucleotides, particularly in research, the reagents segment experiences a parallel surge in growth, highlighting their vital role in generating accurate and reliable results for various molecular biology applications. Furthermore, constant advancements in reagent technologies contribute to the overall advancement of this field.

Global Oligonucleotide Synthesis Market: By End User

Based on end user, the market is segmented into hospitals, pharmaceutical companies, diagnostic laboratories, and others. The pharmaceutical companies segment is expected to be the largest during the forecast period. Pharmaceutical companies rely heavily on oligonucleotide synthesis for preclinical and clinical research, including identifying and validating potential drug targets and developing nucleic acid-based therapeutics. Also, the continuous advances in oligonucleotide synthesis technology allow the synthesis of complex and variable sequences, thereby supporting the industry's search for innovative therapeutic solutions.

The diagnostic laboratories are expected to be the fastest-growing segment in the global oligonucleotide synthesis market during the forecast period. This is due to the growing demand for oligonucleotide synthesis in molecular diagnostics for various applications like genetic mutation detection and PCR primers. These applications have caused a rapid growth of the segment in the global oligonucleotide synthesis market.

asia pacific oligonucleotide synthesis market

Global Oligonucleotide Synthesis Market: By Region

North America is expected to hold the largest regional market share in the global oligonucleotide synthesis market during the forecast period. The region is home to many top companies, such as Danaher, Stryker, and Thermo Fisher Scientific, which contribute a significant global market share. Also, the region has a favorable regulatory landscape for the growth of the global market. In 2022, the U.S. HHS published a guide called “Screening Framework Guidance for Providers and Users of Synthetic Oligonucleotides,” which outlined all the policies and regulations concerning oligonucleotide synthesis.

Asia Pacific is expected to be the fastest-growing region in the global oligonucleotide synthesis market during the forecast period. This is owing to the rapid growth of the biotechnology sector in India, China, and Japan. Moreover, the region has a significant population affected by chronic diseases, which increases the demand for oligonucleotide therapies. Government initiatives like the “Genome India Project,” which was launched by the Indian Department of Biotechnology in January 2020, also act as drivers for the growth of the oligonucleotide synthesis market in the region. Furthermore, collaboration between companies in APAC and other regions has served to fuel the market growth. For instance, in 2022, Vanda Pharmaceuticals collaborated with Olipass Corporation to develop antisense oligonucleotide therapeutics.

Global Oligonucleotide Synthesis Market Share and Competitor Analysis

Key players operating in the global oligonucleotide synthesis market include Danaher Corp., Thermo Fisher Scientific, Eurofins Scientific, Biogen Inc., LGC Ltd., Merck KGaA, Kaneka Corp., Agilent Technologies, Alnylam Pharmaceuticals, and Sarepta Therapeutics, among others.

Please note: This is not an exhaustive list of companies profiled in the report.

Global Oligonucleotide Synthesis Market: Recent Developments

In January 2024, Vanda Pharmaceuticals Inc. (Vanda) announced that the U.S. Food and Drug Administration (FDA) approved the investigational new drug (IND) VCA-894A, a novel antisense oligonucleotide candidate for treating a patient with Charcot-Marie-Tooth disease, axonal, type 2S (CMT2S), caused by cryptic splice site variants within the IGHMBP2 gene.

In September 2022, EnPlusOne Biosciences, Inc., a biotechnology company synthesizing RNA oligonucleotides using enzymes, raised USD 12 million in seed financing. Northpond Ventures led the round, which also included Breakout Ventures, Coatue, and angel investors.

1          STRATEGIC INSIGHTS ON NEW REVENUE POCKETS

1.1    Strategic Opportunity & Attractiveness Analysis

1.1.1        Hot Revenue Pockets

1.1.2        Market Attractiveness Score

1.1.3        Revenue Impacting Opportunity

1.1.4        High Growing Region/Country

1.1.5        Competitor Analysis

1.1.6        Consumer Analysis

1.2    Global Market Estimates' View

1.3    Strategic Insights across Business Functions

1.3.1        For Chief Executive Officers

1.3.2        For Chief Marketing Officers

1.3.3        For Chief Strategy Officers

1.4    Evaluate the Potential of your Existing Business Lines vs. New Lines to Enter Into

2          TECHNOLOGICAL TRENDS

2.1   Technological Adoption Rate

2.2   Current Trend Impact Analysis

2.3   Future Trend Impact Analysis

3.1   Market Pyramid Analysis

3.1.1        Introduction

3.1.2        Adjacent Market Opportunities

3.1.3        Ancillary Market Opportunities

3.2   Demand Side Analysis

3.2.1        Market Drivers: Impact Analysis

3.2.2        Market Restraints: Impact Analysis

3.2.3        Market Opportunities: Impact Analysis

3.2.4        Market Challenges: Impact Analysis

3.3   Supply Side Analysis

3.3.1        Porter’s Five Forces Analysis

3.3.1.1 Threat of New Entrants

3.3.1.2 Threat of New Substitutes

3.3.1.3 Bargaining Power of Suppliers

3.3.1.4 Bargaining Power of Buyers

3.3.1.5 Intensity of Competitive Rivalry

3.3.2        SWOT Analysis; By Factor (Political & Legal, Economic, and Technological)

3.3.2.1 Political Landscape

3.3.2.2 Economic Landscape

3.3.2.3 Social Landscape

3.3.2.4 Technology Landscape

3.3.3        Value Chain Analysis

3.3.4        Trend Analysis

3.3.5        Gap Analysis

3.3.6        Cost Analysis

4          GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET, BY END USER

4.1   Introduction

4.2   Oligonucleotide Synthesis Market: End User Scope Key Takeaways

4.3   Revenue Growth Analysis, 2023 & 2029

4.4   Hospitals

4.4.1        Hospitals Market Estimates and Forecast, 2021-2029 (USD Billion)

4.5   Pharmaceutical Companies

4.5.1        Pharmaceutical Companies Market Estimates and Forecast, 2021-2029 (USD Billion)

4.6   Diagnostic Laboratories

4.6.1        Diagnostic Laboratories Market Estimates and Forecast, 2021-2029 (USD Billion)

4.7   Others

4.7.1        Others Market Estimates and Forecast, 2021-2029 (USD Billion)

5          GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET, BY PRODUCT TYPE

5.1   Introduction

5.2   Oligonucleotide Synthesis Market: Product Type Scope Key Takeaways

5.3   Revenue Growth Analysis, 2023 & 2029

5.4   Oligonucleotide-based Drugs

5.4.1        Oligonucleotide-based Drugs Market Estimates and Forecast, 2021-2029 (USD Billion)

5.5   Synthesized Oligonucleotides

5.5.1        Synthesized Oligonucleotides Market Estimates and Forecast, 2021-2029 (USD Billion)

5.6   Reagents

5.6.1        Reagents Market Estimates and Forecast, 2021-2029 (USD Billion)

5.7   Equipment

5.7.1        Equipment Market Estimates and Forecast, 2021-2029 (USD Billion)

6          GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET, BY APPLICATION TYPE

6.1   Introduction

6.2   Oligonucleotide Synthesis Market: Application Type Scope Key Takeaways

6.3   Revenue Growth Analysis, 2023 & 2029

6.4   Research

6.4.1        Research Market Estimates and Forecast, 2021-2029 (USD Billion)

6.5   Therapeutics

6.5.1        Therapeutics Market Estimates and Forecast, 2021-2029 (USD Billion)

6.6   Diagnostics

6.6.1        Diagnostics Market Estimates and Forecast, 2021-2029 (USD Billion)

7          GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET, BY REGION

7.1   Introduction

7.2   North America Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.2.1        By End User

7.2.2        By Product Type

7.2.3        By Application Type

7.2.4        By Country

7.2.4.1     U.S. Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.2.4.1.1        By End User

7.2.4.1.2        By Product Type

7.2.4.1.3        By Application Type

7.2.4.2     Canada Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.2.4.2.1        By End User

7.2.4.2.2        By Product Type

7.2.4.2.3        By Application Type

7.2.4.3     Mexico Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.2.4.3.1        By End User

7.2.4.3.2        By Product Type

7.2.4.3.3        By Application Type

7.3   Europe Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.3.1        By End User

7.3.2        By Product Type

7.3.3        By Application Type

7.3.4        By Country

7.3.4.1     Germany Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.3.4.1.1        By End User

7.3.4.1.2        By Product Type

7.3.4.1.3        By Application Type

7.3.4.2     U.K. Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.3.4.2.1        By End User

7.3.4.2.2        By Product Type

7.3.4.2.3        By Application Type

7.3.4.3     France Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.3.4.3.1        By End User

7.3.4.3.2        By Product Type

7.3.4.3.3        By Application Type

7.3.4.4     Italy Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.3.4.4.1        By End User

7.3.4.4.2        By Product Type

7.2.4.4.3        By Application Type

7.3.4.5     Spain Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.3.4.5.1        By End User

7.3.4.5.2        By Product Type

7.2.4.5.3        By Application Type

7.3.4.6     Netherlands Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.3.4.7.1        By End User

7.3.4.7.2        By Product Type

7.2.4.7.3        By Application Type

7.3.4.7     Rest of Europe Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.3.4.7.1        By End User

7.3.4.7.2        By Product Type

7.2.4.7.3        By Application Type

7.4   Asia Pacific Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.1        By End User

7.4.2        By Product Type

7.4.3        By Application Type

7.4.4        By Country

7.4.4.1     China Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.1.1        By End User

7.4.4.1.2        By Product Type

7.4.4.1.3        By Application Type

7.4.4.2     Japan Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.2.1        By End User

7.4.4.2.2        By Product Type

7.4.4.2.3        By Application Type

7.4.4.3     India Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.3.1        By End User

7.4.4.3.2        By Product Type

7.4.4.3.3        By Application Type

7.4.4.4     South Korea Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.4.1        By End User

7.4.4.4.2        By Product Type

7.4.4.4.3        By Application Type

7.4.4.5     Singapore Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.5.1        By End User

7.4.4.5.2        By Product Type

7.4.4.5.3        By Application Type

7.4.4.6     Malaysia Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.7.1        By End User

7.4.4.7.2        By Product Type

7.4.4.7.3        By Application Type

7.4.4.7     Thailand Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.7.1        By End User

7.4.4.7.2        By Product Type

7.4.4.7.3        By Application Type

7.4.4.8     Indonesia Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.8.1        By End User

7.4.4.8.2        By Product Type

7.4.4.8.3        By Application Type

7.4.4.9     Vietnam Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.9.1        By End User

7.4.4.9.2        By Product Type

7.4.4.9.3        By Application Type

7.4.4.10  Taiwan Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.10.1 By End User

7.4.4.10.2 By Product Type

7.4.4.10.3 By Application Type

7.4.4.11  Rest of Asia Pacific Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.4.4.11.1 By End User

7.4.4.11.2 By Product Type

7.4.4.11.3 By Application Type

7.5   Middle East and Africa Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.5.1        By End User

7.5.2        By Product Type

7.5.3        By Application Type

7.5.4        By Country

7.5.4.1     Saudi Arabia Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.5.4.1.1        By End User

7.5.4.1.2        By Product Type

7.5.4.1.3        By Application Type

7.5.4.2     U.A.E. Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.5.4.2.1        By End User

7.5.4.2.2        By Product Type

7.5.4.2.3        By Application Type

7.5.4.3     Israel Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.5.4.3.1        By End User

7.5.4.3.2        By Product Type

7.5.4.3.3        By Application Type

7.5.4.4     South Africa Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.5.4.4.1        By End User

7.5.4.4.2        By Product Type

7.5.4.4.3        By Application Type

7.5.4.5     Rest of Middle East and Africa Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.5.4.5.1        By End User

7.5.4.5.2        By Product Type

7.5.4.5.2        By Application Type

7.6   Central and South America Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.7.1        By End User

7.7.2        By Product Type

7.7.3        By Application Type

7.7.4        By Country

7.7.4.1     Brazil Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.7.4.1.1        By End User

7.7.4.1.2        By Product Type

7.7.4.1.3        By Application Type

7.7.4.2     Argentina Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.7.4.2.1        By End User

7.7.4.2.2        By Product Type

7.7.4.2.3        By Application Type

7.7.4.3     Chile Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.7.4.3.1        By End User

7.7.4.3.2        By Product Type

7.7.4.3.3        By Application Type

7.7.4.4     Rest of Central and South America Oligonucleotide Synthesis Market Estimates and Forecast, 2021-2029 (USD Billion)

7.7.4.4.1        By End User

7.7.4.4.2        By Product Type

7.7.4.4.3        By Application Type

8          COMPETITIVE LANDCAPE

8.1   Company Market Share Analysis

8.2   Four Quadrant Positioning Matrix

8.2.1        Market Leaders

8.2.2        Market Visionaries

8.2.3        Market Challengers

8.2.4        Niche Market Players

8.3   Vendor Landscape

8.3.1        North America

8.3.2        Europe

8.3.3        Asia Pacific

8.3.4        Rest of the World

8.4   Company Profiles  

8.4.1        Danaher Corp.

8.4.1.1 Business Description & Financial Analysis

8.4.1.2 SWOT Analysis

8.4.1.3 Products & Services Offered

8.4.1.4 Strategic Alliances between Business Partners

8.4.2        Kaneka Corp.  

8.4.2.1 Business Description & Financial Analysis

8.4.2.2 SWOT Analysis

8.4.2.3 Products & Services Offered

8.4.2.4 Strategic Alliances between Business Partners

8.4.3        Thermo Fisher Scientific

8.4.3.1 Business Description & Financial Analysis

8.4.3.2 SWOT Analysis

8.4.3.3 Products & Services Offered

8.4.3.4 Strategic Alliances between Business Partners

8.4.4        Merck KGaA

8.4.4.1 Business Description & Financial Analysis

8.4.4.2 SWOT Analysis

8.4.4.3 Products & Services Offered

8.4.4.4 Strategic Alliances between Business Partners

8.4.5        LGC Ltd.

8.4.5.1 Business Description & Financial Analysis

8.4.5.2 SWOT Analysis

8.4.5.3 Products & Services Offered

8.4.5.4 Strategic Alliances between Business Partners

8.4.6        Eurofins Scientific

8.4.7.1 Business Description & Financial Analysis

8.4.7.2 SWOT Analysis

8.4.7.3 Products & Services Offered

8.4.7.4 Strategic Alliances between Business Partners

8.4.7        Agilent Technologies  

8.4.7.1 Business Description & Financial Analysis

8.4.7.2 SWOT Analysis

8.4.7.3 Products & Services Offered

8.4.8.4 Strategic Alliances between Business Partners

8.4.8        Sarepta Therapeutics

8.4.8.1 Business Description & Financial Analysis

8.4.8.2 SWOT Analysis

8.4.8.3 Products & Services Offered

8.4.8.4 Strategic Alliances between Business Partners

8.4.9        Alnylam Pharmaceuticals

8.4.9.1 Business Description & Financial Analysis

8.4.9.2 SWOT Analysis

8.4.9.3 Products & Services Offered

8.4.9.4 Strategic Alliances between Business Partners

8.4.10      Biogen Inc.

8.4.10.1 Business Description & Financial Analysis

8.4.10.2 SWOT Analysis

8.4.10.3 Products & Services Offered

8.4.10.4 Strategic Alliances between Business Partners

8.4.11      Other Companies

8.4.11.1 Business Description & Financial Analysis

8.4.11.2 SWOT Analysis

8.4.11.3 Products & Services Offered

8.4.11.4 Strategic Alliances between Business Partners

9          RESEARCH OFFERINGOLOGY

9.1   Market Introduction

9.1.1        Market Definition

9.1.2        Market Scope & Segmentation

9.2   Information Procurement

9.2.1        Secondary Research

9.2.1.1 Purchased Databases

9.2.1.2 GMEs Internal Data Repository

9.2.1.3 Secondary Resources & Third Party Perspectives

9.2.1.4 Company Information Sources

9.2.2        Primary Research

9.2.2.1 Various Types of Respondents for Primary Interviews

9.2.2.2 Number of Interviews Conducted throughout the Research Process

9.2.2.3 Primary Stakeholders

9.2.2.4 Discussion Guide for Primary Participants

9.2.3        Expert Panels

9.2.3.1 Expert Panels Across 30+ Industry

9.2.4        Paid Local Experts

9.2.4.1 Paid Local Experts Across 30+ Industry Across each Region

9.3   Market Estimation

9.3.1        Top-Down Approach

9.3.1.1 Macro-Economic Indicators Considered

9.3.1.2 Micro-Economic Indicators Considered

9.3.2        Bottom Up Approach

9.3.2.1 Company Share Analysis Approach

9.3.2.2 Estimation of Potential Product Sales

9.4   Data Triangulation

9.4.1        Data Collection

9.4.2        Time Series, Cross Sectional & Panel Data Analysis

9.4.3        Cluster Analysis

9.5   Analysis and Output

9.5.1        Inhouse AI Based Real Time Analytics Tool

9.5.2        Output From Desk & Primary Research

9.6   Research Assumptions & Limitations

9.7.1        Research Assumptions

9.7.2        Research Limitations

LIST OF TABLES

1 Global Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

2 Hospitals Market, By Region, 2021-2029 (USD Billion)         

3 Pharmaceutical Companies Market, By Region, 2021-2029 (USD Billion)  

4 Diagnostic Laboratories Companies Market, By Region, 2021-2029 (USD Billion)

5 Others Oligonucleotide Synthesis Market, By Region, 2021-2029 (USD Billion)  

6 Global Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

7 Oligonucleotide-based Drugs Market, By Region, 2021-2029 (USD Billion)           

8 Synthesized Oligonucleotides Market, By Region, 2021-2029 (USD Billion)

9 Reagents Market, By Region, 2021-2029 (USD Billion)

10 Equipment Market, By Region, 2021-2029 (USD Billion)

11 Global Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

12 Research Market, By Region, 2021-2029 (USD Billion)          

13 Therapeutics Market, By Region, 2021-2029 (USD Billion)

14 Diagnostics Market, By Region, 2021-2029 (USD Billion)

15 Regional Analysis, 2021-2029 (USD Billion)               

16 North America Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

17 North America Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

18 North America Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

19 North America Oligonucleotide Synthesis Market, By Country, 2021-2029 (USD Billion)

20 U.S. Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

21 U.S. Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

22 U.S. Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

23 Canada Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

24 Canada Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

25 Canada Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

26 Mexico Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

27 Mexico Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

28 Mexico Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

29 Europe Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

30 Europe Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

31 Europe Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

32 EUROPE Oligonucleotide Synthesis Market, By Country, 2021-2029 (USD Billion)

33 Germany Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

34 Germany Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

35 Germany Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

36 U.K. Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

37 U.K. Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

38 U.K. Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

39 France Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

40 France Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

41 France Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

42 Italy Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

43 Italy Oligonucleotide Synthesis Market, By Product Type Type, 2021-2029 (USD Billion)

44 Italy Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

45 Spain Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

46 Spain Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

47 Spain Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

48 Netherland Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

49 Netherland Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

50 Netherland Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

51 Rest Of Europe Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

52 Rest Of Europe Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

53 Rest of Europe Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

54 Asia Pacific Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

55 Asia Pacific Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

56 Asia Pacific Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

57 Asia Pacific Oligonucleotide Synthesis Market, By Country, 2021-2029 (USD Billion)

58 China Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

59 China Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

60 China Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

61 India Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

62 India Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

63 India Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

64 Japan Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

65 Japan Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

66 Japan Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

67 South Korea Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

68 South Korea Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

69 South Korea Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

70 Australia Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

71 Australia Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

72 Australia Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

73 Thailand Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

74 Thailand Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

75 Thailand Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

76 Vietnam Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

77 Vietnam Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

78 Vietnam Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

79 indonesia Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

80 indonesia Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

81 indonesia Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

82 Malaysia Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

83 Malaysia Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

84 Malaysia Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

85 Philippines Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

86 Philippines Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

87 Philippines Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

88 Singapore Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

89 Singapore Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

90 Singapore Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

91 Rest of APAC Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

92 Rest of APAC Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

93 Rest of APAC Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

94 Middle East and Africa Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

95 Middle East and Africa Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

96 Middle East and Africa Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

97 Middle East and Africa Oligonucleotide Synthesis Market, By Country, 2021-2029 (USD Billion)

98 Saudi Arabia Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

99 Saudi Arabia Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

100 Saudi Arabia Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

101 UAE Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

102 UAE Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

103 UAE Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

104 South Africa Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

105 South Africa Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

106 South Africa Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

107 Israel Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

108 Israel Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

109 Israel Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

110 Rest of Middle East and Africa Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

111 Rest of Middle East and Africa Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

112 Rest of Middle East and Africa Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

113 Central and South America Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

114 Central and South America Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

115 Central and South America Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

116 Central and South America Oligonucleotide Synthesis Market, By Country, 2021-2029 (USD Billion)

117 Brazil Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

118 Brazil Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

119 Brazil Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

120 Argentina Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

121 Argentina Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

122 Argentina Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

123 Chile Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

124 Chile Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

125 Chile Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

126 Rest of Central and South America Oligonucleotide Synthesis Market, By End User, 2021-2029 (USD Billion)

127 Rest of Central and South America Oligonucleotide Synthesis Market, By Product Type, 2021-2029 (USD Billion)

128 Rest of Central and South America Oligonucleotide Synthesis Market, By Application Type, 2021-2029 (USD Billion)

129 DANAHER CORP.: Products & Services Offering

130 KANEKA CORP. : Products & Services Offering           

131 Thermo Fisher Scientific: Products & Services Offering   

132 Merck KGaA: Products & Services Offering

133 LGC Ltd.: Products & Services Offering        

134 EUROFINS SCIENTIFIC: Products & Services Offering               

135 Agilent Technologies : Products & Services Offering        

136 Sarepta Therapeutics: Products & Services Offering          

137 Alnylam Pharmaceuticals: Products & Services Offering               

138 Biogen Inc.: Products & Services Offering 

139 Other Companies: Products & Services Offering    

LIST OF FIGURES

1 Global Oligonucleotide Synthesis Market Overview

2 Global Oligonucleotide Synthesis Market Value From 2021-2029 (USD Billion)

3 Global Oligonucleotide Synthesis Market Share, By End User (2023)

4 Global Oligonucleotide Synthesis Market Share, By Product Type (2023)

5 Global Oligonucleotide Synthesis Market Share, By Application Type (2023)

6 Global Oligonucleotide Synthesis Market, By Region (Asia Pacific Market)

7 Technological Trends In Global Oligonucleotide Synthesis Market

8 Four Quadrant Competitor Positioning Matrix

9 Impact Of Macro & Micro Indicators On The Market

10 Impact Of Key Drivers On The Global Oligonucleotide Synthesis Market

11 Impact Of Challenges On The Global Oligonucleotide Synthesis Market

12 Porter’s Five Forces Analysis

13 Global Oligonucleotide Synthesis Market: By End User Scope Key Takeaways

14 Global Oligonucleotide Synthesis Market, By End User Segment: Revenue Growth Analysis

15 Hospitals Market, By Region, 2021-2029 (USD Billion)

16 Pharmaceutical Companies Market, By Region, 2021-2029 (USD Billion)

17 Diagnostic Laboratories Companies Market, By Region, 2021-2029 (USD Billion)

18 Others Market, By Region, 2021-2029 (USD Billion)   

19 Global Oligonucleotide Synthesis Market: By Product Type Scope Key Takeaways

20 Global Oligonucleotide Synthesis Market, By Product Type Segment: Revenue Growth Analysis

21 Oligonucleotide-based Drugs Market, By Region, 2021-2029 (USD Billion)

22 Synthesized Oligonucleotides Market, By Region, 2021-2029 (USD Billion)

23 Reagents Market, By Region, 2021-2029 (USD Billion)

24 Equipment Market, By Region, 2021-2029 (USD Billion)

25 Global Oligonucleotide Synthesis Market: By Application Type Scope Key Takeaways

26 Global Oligonucleotide Synthesis Market, By Application Type Segment: Revenue Growth Analysis

27 Research Market, By Region, 2021-2029 (USD Billion)

28 Therapeutics Market, By Region, 2021-2029 (USD Billion)

29 Diagnostics Market, By Region, 2021-2029 (USD Billion)

30 Regional Segment: Revenue Growth Analysis

31 Global Oligonucleotide Synthesis Market: Regional Analysis

32 North America Oligonucleotide Synthesis Market Overview

33 North America Oligonucleotide Synthesis Market, By End User

34 North America Oligonucleotide Synthesis Market, By Product Type

35 North America Oligonucleotide Synthesis Market, By Application Type

36 North America Oligonucleotide Synthesis Market, By Country

37 U.S. Oligonucleotide Synthesis Market, By End User

38 U.S. Oligonucleotide Synthesis Market, By Product Type

39 U.S. Oligonucleotide Synthesis Market, By Application Type

40 Canada Oligonucleotide Synthesis Market, By End User

41 Canada Oligonucleotide Synthesis Market, By Product Type

42 Canada Oligonucleotide Synthesis Market, By Application Type

43 Mexico Oligonucleotide Synthesis Market, By End User

44 Mexico Oligonucleotide Synthesis Market, By Product Type

45 Mexico Oligonucleotide Synthesis Market, By Application Type

46 Four Quadrant Positioning Matrix

47 Company Market Share Analysis

48 Danaher Corp.: Company Snapshot

49 Danaher Corp.: SWOT Analysis

50 Danaher Corp.: Geographic Presence

51 Kaneka Corp. : Company Snapshot

52 Kaneka Corp. : SWOT Analysis

53 Kaneka Corp. : Geographic Presence

54 Thermo Fisher Scientific: Company Snapshot

55 Thermo Fisher Scientific: SWOT Analysis

56 Thermo Fisher Scientific: Geographic Presence

57 Merck KGaA: Company Snapshot

58 Merck KGaA: Swot Analysis

59 Merck KGaA: Geographic Presence

60 LGC Ltd.: Company Snapshot

61 LGC Ltd.: SWOT Analysis

62 LGC Ltd.: Geographic Presence

63 Eurofins Scientific: Company Snapshot

64 Eurofins Scientific: SWOT Analysis

65 Eurofins Scientific: Geographic Presence

66 Agilent Technologies : Company Snapshot

67 Agilent Technologies : SWOT Analysis

68 Agilent Technologies : Geographic Presence

69 Sarepta Therapeutics: Company Snapshot

70 Sarepta Therapeutics: SWOT Analysis

71 Sarepta Therapeutics: Geographic Presence

72 Alnylam Pharmaceuticals: Company Snapshot

73 Alnylam Pharmaceuticals: SWOT Analysis

74 Alnylam Pharmaceuticals: Geographic Presence

75 Biogen Inc.: Company Snapshot

76 Biogen Inc.: SWOT Analysis

77 Biogen Inc.: Geographic Presence

78 Other Companies: Company Snapshot

79 Other Companies: SWOT Analysis

80 Other Companies: Geographic Presence

The Global Oligonucleotide Synthesis Market has been studied from the year 2019 till 2029. However, the CAGR provided in the report is from the year 2024 to 2029. The research methodology involved three stages: Desk research, Primary research, and Analysis & Output from the entire research process.

Oligonucleotide Synthesis Market Size

The desk research involved a robust background study which meant referring to paid and unpaid databases to understand the market dynamics; mapping contracts from press releases; identifying the key players in the market, studying their product portfolio, competition level, annual reports/SEC filings & investor presentations; and learning the demand and supply-side analysis for the Oligonucleotide Synthesis Market.

Oligonucleotide Synthesis Market Growth

The primary research activity included telephonic conversations with more than 50 tier 1 industry consultants, distributors, and end-use product manufacturers.

Oligonucleotide Synthesis Market Trends

Finally, based on the above thorough research process, an in-depth analysis was carried out considering the following aspects: market attractiveness, current & future market trends, market share analysis, SWOT analysis of the company and customer analytics.

Oligonucleotide Synthesis Market Share

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Frequently Asked Questions

The global oligonucleotide synthesis market is expected to grow at a CAGR of 16.4% from 2024 to 2029.
Key players operating in the global oligonucleotide synthesis market include Danaher Corp., Thermo Fisher Scientific, Eurofins Scientific, Biogen Inc., LGC Ltd., Merck KGaA, Kaneka Corp., Agilent Technologies, Alnylam Pharmaceuticals, and Sarepta Therapeutics, among others.
Companies have significant growth opportunities in the oligonucleotide synthesis market by investing in innovative technologies, expanding therapeutic applications, and enhancing production efficiency to meet the rising demand for personalized medicine and genetic diagnostics.
The global oligonucleotide synthesis market growth is driven by the increasing prevalence of chronic diseases, necessitating oligonucleotide therapeutics. Oligonucleotide synthesis is also vital for molecular diagnosis, detecting genetic disorders through techniques like PCR and RT-PCR.

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