Plasmid DNA Manufacturing Market

Global Plasmid DNA Manufacturing Market Size, Trends & Analysis - Forecasts to 2027 By Step Scope (Process Development, cGMP Manufacturing, QC and Analytical, Others), By Scale Scope (Research-Grade Plasmid, Industrial Grade, Others), By Application Scope (Cell & Gene Therapy Manufacturing, Vaccines Development, Viral Vector Manufacturing, Research Applications), By End-use Scope (Pharmaceutical and Biopharmaceutical Companies, Government & Academic Research Institutes), By Region (North America, Asia Pacific, CSA, Europe, and the Middle East and Africa), Company Market Share Analysis, and Competitor Analysis

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This report was recently updated on October 4 2024 with the latest and most recent market numbers

Plasmid DNA Manufacturing Market Size

The Global Plasmid DNA Manufacturing Market is projected to grow at a CAGR value of 24.5% from 2022 to 2027.

Gene therapy and genetic vaccination are medical techniques that have reformed human life significantly and are gaining prominence due to their various uses in treating diseases. Plasmid DNA is a gene therapy product that uses genetically engineered circular DNA molecules to carry therapeutic genes into human cells. Plasmid DNA also is a crucial starting material for advanced therapies such as RNA vaccines and viral vectors.

The global plasmid DNA manufacturing market is expected to proliferate due to the rising demand for plasmid DNA in various medical therapies, increasingly successful clinical outcomes of using plasmid DNA in medical procedures, the growing prevalence of people suffering from multiple diseases and rapid growth advancements in the biopharmaceutical industry.

Furthermore, rising government investments in the healthcare sector and an increasing population of older adults are additional factors that will boost the plasmid DNA manufacturing market.

The COVID-19 pandemic has hugely affected the healthcare industry and has made it necessary for the sector to think of innovative ways to handle the pandemic through innovative drugs. Plasmid DNA has been increasingly used for new vaccine innovations, and has the property that can stimulate the immune system upon reaching it.

Plasmid DNA-based vaccines have given rise to innovations such as ZyCoV-D, extensively used to build immunity among people. The additional benefit of a plasmid DNA-based vaccine compared to other types of vaccines is that plasmid DNA vaccines are relatively safe, stable and cost-effective. Scientists have also found that the plasmid DNA vaccines can last for months and be stored at higher temperatures. The pandemic has acted as an incentive for manufacturers to produce plasmid DNA-based products.

global plasmid dna manufacturing market

Plasmid DNA Manufacturing Market: By Step Scope

Based on the step scope, the plasmid DNA manufacturing market is divided into process development, cGMP manufacturing, QC, and analytical. The cGMP manufacturing segment is expected to be the fastest-growing segment in the market from 2022 to 2027.

cGMP manufacturing has been gaining prominence due to consumers’ increased expectations for quality drugs and vaccines. The Food and Drugs Administration (FDA) has instructed pharmaceutical product manufacturers to adhere to the cGMP regulations. Adherence to the rules would mean safer, unadulterated and rising prevalence of cancer patients, growing demand for health procedures that are safe and efficient, and key players in the market.

Furthermore, increasing technological developments in the healthcare sector and the newfound knowledge on the use of plasmid DNA will propel the plasmid DNA manufacturing market.

Plasmid DNA Manufacturing Market: By Scale Scope

The plasmid DNA Manufacturing market is divided into a research-grade plasmid, industrial grade, and others based on the scale scope. The research-grade segment is expected to be the largest segment in the market from 2022 to 2027. Research grade plasmid DNA is used in multiple procedures such as re-cloning, transformation and sequencing of standard DNA and hence is in demand when it comes to the cancer drug discovery field.

Plasmid DNA Manufacturing Market: By Application Scope

The plasmid DNA Manufacturing market is divided into cell & gene therapy manufacturing, vaccines development, viral vector manufacturing, and research applications based on the application scope. The cell and gene therapy manufacturing segment is expected to be the largest segment in the market from 2022 to 2027.

Gene therapy is used in cell modification and reconstructing genetic material that is defective in nature. Cell and gene therapy has been widely used in the medical field to treat genetic disorders. Gene therapies also help in diagnosing viral diseases and conditions in people.

Plasmid DNA Manufacturing Market: By End-use Scope

The Plasmid DNA Manufacturing market is divided into pharmaceutical and biopharmaceutical companies, government and academic research institutes based on the end-use scope. The pharmaceutical and biopharmaceutical companies segment is expected to be the fastest-growing segment in the market from 2022 to 2027.

Plasmid DNA plays a pivotal role in products manufactured by pharmaceutical and biopharmaceutical companies. Pharmaceutical and biopharmaceutical companies use plasmid DNA for toxicology studies and pre-clinical research. Companies have also increased their investments owing to the viable nature of plasmid DNA and growing consumer demand.

asia pacific plasmid dna manufacturing market

Plasmid DNA Manufacturing Market: By Region

As per the geographical analysis, the plasmid DNA manufacturing market can be classified into North America (the United States, Canada, and Mexico), Asia Pacific (India, China, Japan, Malaysia, Singapore, and the Rest of Asia Pacific), Europe (Germany, United Kingdom, Italy, France, Spain, Netherlands, and Rest of Europe), Middle East & Africa (Saudi Arabia, United Arab Emirates, and Rest of the Middle East & Africa) and Central & South America (Brazil, Argentina, and Rest of Central and South America).

North America (the United States, Canada, and Mexico) will dominate the Plasmid DNA Manufacturing market from 2022 to 2027. The primary factor driving the growth of the market in the North American region is the rising prevalence of cancer patients, the growing demand for health procedures that are safe and efficient and the presence of key players in the market.

Furthermore, increasing technological developments in the healthcare sector and the newfound knowledge on the use of plasmid DNA will propel the plasmid DNA manufacturing market.

Moreover, the Asia Pacific (India, China, Japan, Malaysia, Singapore, and the Rest of Asia Pacific) region is expected to be the fastest-growing segment in the Plasmid DNA Manufacturing market during the forecast period. The rapidly rising geriatric population, increasing cases of disease-ridden patients, and government initiatives in deploying plasmid DNA-based products are the factors that will boost plasmid DNA manufacturing in the region.

Plasmid DNA Manufacturing Market Share and Competitor Analysis

Thermo Fisher Scientific, Inc., Boehringer Ingelheim Biopharmaceuticals GmbH, Charles River Laboratories, Aidevron, Sartorius AG, Kaneka Eurogentec S.A., Catalent, Inc., Vigene Biosciences, Creative Biogene and VGXI, Inc. among others are the key players in the plasmid DNA manufacturing market.

Please note: This is not an exhaustive list of companies profiled in the report.

Chapter 1   Methodology

1.1    Market Scope & Definitions

1.2    Estimates & Forecast Calculation

1.3    Historical Data Overview and Validation

1.4    Data Sources

1.4.1    Secondary

1.4.2    Primary

Chapter 2   Report Outlook

2.1    Plasmid DNA Manufacturing Industry Overview, 2022-2027

2.1.1    Industry Overview

2.1.2    Step Scope Overview

2.1.3    Scale Scope Overview

2.1.4    Application Scope Overview

2.1.5    End-use Scope Overview

2.1.6    Regional Overview

Chapter 3   Plasmid DNA Manufacturing Market Trends

3.1    Market Segmentation

3.2    Industry Background, 2022-2027

3.3    Market Key Trends

3.3.1    Positive Trends

3.3.1.1    Advancements in the plasmid DNA based products

3.3.1.2    Growing geriatric population in the APAC region

3.3.2    Industry Challenges

3.3.2.1    Lack of adequate infrastructure in developing nations

3.4    Prospective Growth Scenario

3.4.1    Step Scope Growth Scenario

3.4.2    Scale Scope Growth Scenario

3.4.3    Application Scope Growth Scenario

3.4.4    End-use Scope Growth Scenario

3.5    COVID-19 Influence over Industry Growth

3.6    Porter’s Analysis

3.7    PESTEL Analysis

3.8    Value Chain & Supply Chain Analysis

3.9    Regulatory Framework

3.9.1    North America

3.9.2    Europe

3.9.3    APAC

3.9.4    LATAM

3.9.5    MEA

3.10    End-use Scope Overview

3.11    Market Share Analysis, 2022

3.11.1    Company Positioning Overview, 2022

Chapter 4   Plasmid DNA Manufacturing Market, By Step Scope

4.1    Step Scope Outlook

4.2    Process Development

4.2.1    Market Size, By Region, 2022-2027 (USD Million)

4.3    cGMP Manufacturing

4.3.1    Market Size, By Region, 2022-2027 (USD Million)

4.4    QC and Analytical

4.4.1    Market Size, By Region, 2022-2027 (USD Million)

4.5    Others

4.5.1    Market Size, By Region, 2022-2027 (USD Million)

Chapter 5   Plasmid DNA Manufacturing Market, By Application Scope

5.1    Application Scope Outlook

5.2    Cell & Gene Therapy Manufacturing

5.2.1    Market Size, By Region, 2022-2027 (USD Million)

5.3    Vaccine Development

5.3.1    Market Size, By Region, 2022-2027 (USD Million)

5.4    Viral Vector Manufacturing

5.4.1    Market Size, By Region, 2022-2027 (USD Million)

5.5    Research Applications

5.5.1    Market Size, By Region, 2022-2027 (USD Million)

Chapter 6   Plasmid DNA Manufacturing Market, By Scale Scope

6.1    Research-Grade Plasmid

6.1.1    Market Size, By Region, 2022-2027 (USD Million)

6.2    Industrial Grade

6.2.1    Market Size, By Region, 2022-2027 (USD Million)

Chapter 7   Plasmid DNA Manufacturing Market, By End-use Scope

7.1    Pharmaceutical and Biopharmaceutical Companies

7.1.1    Market Size, By Region, 2022-2027 (USD Million)

7.2    Government & Academic Research Institutes

7.2.1    Market Size, By Region, 2022-2027 (USD Million)

Chapter 8   Plasmid DNA Manufacturing Market, By Region

8.1    Regional outlook

8.2    North America

8.2.1    Market Size, By Country 2022-2027 (USD Million)

8.2.2    Market Size, By Step Scope, 2022-2027 (USD Million)

8.2.3    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.2.4    Market Size, By Application Scope, 2022-2027 (USD Million)

8.2.5    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.2.6    U.S.

8.2.6.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.2.4.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.2.4.3    Market Size, By Application Scope, 2022-2027 (USD Million)

Market Size, By End-use Scope, 2022-2027 (USD Million)

8.2.7    Canada

8.2.7.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.2.7.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.2.7.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.2.7.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.3    Europe

8.3.1    Market Size, By Country 2022-2027 (USD Million)

8.3.2    Market Size, By Step Scope, 2022-2027 (USD Million)

8.3.3    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.3.4    Market Size, By Application Scope, 2022-2027 (USD Million)

8.3.5    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.3.6    Germany

8.3.6.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.3.6.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.3.6.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.3.6.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.3.7    UK

8.3.7.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.3.7.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.3.7.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.3.7.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.3.8    France

8.3.8.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.3.8.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.3.8.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.3.8.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.3.9    Italy

8.3.9.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.3.9.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.3.9.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.3.9.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.3.10    Spain

8.3.10.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.3.10.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.3.10.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.3.10.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.3.11    Russia

8.3.11.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.3.11.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.3.11.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.3.11.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.4    Asia Pacific

8.4.1    Market Size, By Country 2022-2027 (USD Million)

8.4.2    Market Size, By Step Scope, 2022-2027 (USD Million)

8.4.3    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.4.4    Market Size, By Application Scope, 2022-2027 (USD Million)

8.4.5   Market Size, By End-use Scope, 2022-2027 (USD Million)

8.4.6    China

8.4.6.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.4.6.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.4.6.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.4.6.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.4.7    India

8.4.7.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.4.7.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.4.7.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.4.7.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.4.8    Japan

8.4.8.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.4.8.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.4.8.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.4.8.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.4.9    Australia

8.4.9.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.4.9.2    Market size, By Scale Scope, 2022-2027 (USD Million)

8.4.9.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.4.9.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.4.10    South Korea

8.4.10.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.4.10.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.4.10.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.4.10.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.5    Central and South America

8.5.1    Market Size, By Country 2022-2027 (USD Million)

8.5.2    Market Size, By Step Scope, 2022-2027 (USD Million)

8.5.3    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.5.4   Market Size, By Application Scope, 2022-2027 (USD Million)

8.5.5   Market Size, By End-use Scope, 2022-2027 (USD Million)

8.5.6    Brazil

8.5.6.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.5.6.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.5.6.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.5.6.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.5.7    Mexico

8.5.7.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.5.7.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.5.7.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.5.7.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.5.8    Argentina

8.5.8.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.5.8.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.5.8.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.5.8.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.6    MEA

8.6.1    Market Size, By Country 2022-2027 (USD Million)

8.6.2    Market Size, By Step Scope, 2022-2027 (USD Million)

8.6.3    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.6.4    Market Size, By Application Scope, 2022-2027 (USD Million)

8.6.5    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.6.6    Saudi Arabia

8.6.6.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.6.6.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.6.6.3   Market Size, By Application Scope, 2022-2027 (USD Million)

8.6.6.4   Market Size, By End-use Scope, 2022-2027 (USD Million)

8.6.7    UAE

8.6.7.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.6.7.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.6.7.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.6.7.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

8.6.8    South Africa

8.6.8.1    Market Size, By Step Scope, 2022-2027 (USD Million)

8.6.8.2    Market Size, By Scale Scope, 2022-2027 (USD Million)

8.6.8.3    Market Size, By Application Scope, 2022-2027 (USD Million)

8.6.8.4    Market Size, By End-use Scope, 2022-2027 (USD Million)

Chapter 9   Company Landscape

9.1    Competitive Analysis, 2022

9.2    Thermo Fisher Scientific, Inc.

9.2.1    Company Overview

9.2.2    Financial Analysis

9.2.3    Strategic Positioning

9.2.4    Info Graphic Analysis

9.3    Boehringer Ingelheim Biopharmaceuticals GmbH

9.3.1    Company Overview

9.3.2    Financial Analysis

9.3.3    Strategic Positioning

9.3.4    Info Graphic Analysis

9.4    Charles River Laboratories

9.4.1    Company Overview

9.4.2    Financial Analysis

9.4.3    Strategic Positioning

9.4.4    Info Graphic Analysis

9.5    Aldevron

9.5.1    Company Overview

9.5.2    Financial Analysis

9.5.3    Strategic Positioning

9.5.4    Info Graphic Analysis

9.6    Sartorius AG

9.6.1    Company Overview

9.6.2    Financial Analysis

9.6.3    Strategic Positioning

9.6.4    Info Graphic Analysis

9.7    Kaneka Eurogentec S.A

9.7.1    Company Overview

9.7.2    Financial Analysis

9.7.3    Strategic Positioning

9.7.4    Info Graphic Analysis

9.8    Catalent, Inc.

9.8.1    Company Overview

9.8.2    Financial Analysis

9.8.3    Strategic Positioning

9.8.4    Info Graphic Analysis

9.9    Vigene Biosciences

9.9.1    Company Overview

9.9.2    Financial Analysis

9.9.3    Strategic Positioning

9.9.4    Info Graphic Analysis

9.10    Creative Biogene

9.10.1    Company Overview

9.10.2    Financial Analysis

9.10.3    Strategic Positioning

9.10.4    Info Graphic Analysis

9.11    VGXI, Inc.

9.11.1    Company Overview

9.11.2    Financial Analysis

9.11.3    Strategic Positioning

9.11.4    Info Graphic Analysis 

The Global Plasmid DNA Manufacturing Market has been studied from the year 2019 till 2027. However, the CAGR provided in the report is from the year 2022 to 2027. The research methodology involved three stages: Desk research, Primary research, and Analysis & Output from the entire research process.

The desk research involved a robust background study which meant referring to paid and unpaid databases to understand the market dynamics; mapping contracts from press releases; identifying the key players in the market, studying their product portfolio, competition level, annual reports/SEC filings & investor presentations; and learning the demand and supply-side analysis for the Plasmid DNA Manufacturing Market.

The primary research activity included telephonic conversations with more than 50 tier 1 industry consultants, distributors, and end-use product manufacturers.

Finally, based on the above thorough research process, an in-depth analysis was carried out considering the following aspects: market attractiveness, current & future market trends, market share analysis, SWOT analysis of the company and customer analytics.

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Frequently Asked Questions

The global plasmid DNA manufacturing market is projected to grow at a CAGR value of 24.5% from 2022 to 2027.
Thermo Fisher Scientific, Inc., Boehringer Ingelheim Biopharmaceuticals GmbH, Charles River Laboratories, Aidevron, Sartorius AG, Kaneka Eurogentec S.A., Catalent, Inc., Vigene Biosciences, Creative Biogene and VGXI, Inc. among others are the key players in the plasmid DNA manufacturing market.
The North American region is estimated to hold the highest share in the plasmid DNA manufacturing market.
The COVID-19 pandemic has hugely affected the healthcare industry and has made it necessary for the sector to think of innovative ways to handle the pandemic. Plasmid DNA has been increasingly used for new vaccine innovations. Plasmid DNA has the property that can stimulate the immune system upon reaching it. Plasmid DNA based vaccines have given rise to new innovations such as ZyCoV-D which are being extensively used to build immunity among people.
The global plasmid DNA manufacturing market is expected to proliferate due to the rising demand for plasmid DNA in various medical therapies, increasingly successful clinical outcomes of using plasmid DNA in medical procedures, the growing prevalence of people suffering from multiple diseases and rapid growth advancements in the biopharmaceutical industry.

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