Global Protein Expression Market

Global Protein Expression Market, Size, Trends & Analysis - Forecasts to 2026 By System Type (Prokaryotic expression systems, Mammalian cell systems, Insect cell systems, Yeast Expression systems, Cell-Free Expression Systems, Algal based expression systems), By Product & Services (Reagents, Expression vectors, Competent cells, Instruments, Services), By Application (Therapeutic, Industrial Application, Research Application), By End Use (Pharmaceutical and biotechnological companies, Academic research, Contract research organizations, Others), By Region (North America, Europe, Asia Pacific and Rest of the World); Vendor Landscape, End User Landscape and Company Market Share Analysis & Competitor Analysis

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This report was recently updated on April 13 2024 with the latest and most recent market numbers

Global Protein Expression Market Insights:

The global protein expression market is expected to generate revenue amounting to USD 2.20 billion in 2020, and is projected to reach to USD 4.66 billion by 2026, growing at a CAGR 13.31% over the forecast period. Increasing incidence of chronic diseases and increasing demand for protein biologics across the globe is driving the market for protein expressions during the forecast period. Protein expression plays an important role in the various applications including therapeutic protein production, biologics production, and research applications among others. Growing demand for novel biologic product for the treatment of cancer, anemia, and multiple sclerosis are driving the market for protein expression during the forecast period.

Growing demand for developing new drugs and vaccines in the pharmaceutical industry is also driving the demand for protein expressions. Increase in R&D activities by many pharmaceuticals, biopharmaceutical, and biotechnology companies to develop and manufacture advanced biologics such as vaccines, monoclonal antibodies, and therapeutic proteins is also boosting the market growth.

Growing chronic diseases across various regions including North America, Europe, Asia Pacific, and Central & South America is further projected to propel the market growth of protein expression. However, the high cost of protein expression reagents and instruments, are likely to hamper the market growth during the forecast period.

Protein Expression Market

Global Protein Expression Market Segmentation:

The global protein expression market is segmented on the basis of system type into prokaryotic expression systems, mammalian cell expression systems, insect cell expression systems, yeast expression systems, cell-free expression systems, and algal-based expression systems. The prokaryotic expression segment is further segmented into escherichia coli systems and other prokaryotic expressions. Prokaryotic expressions are used in many applications and they are produced at high capacity. These expressions are inexpensive compared to other system types. These systems are widely used system for protein overproduction, both on a laboratory and industrial scale. The prokaryotic system allows to produce large quantities of recombinant proteins in a short time. The insect & yeast expression systems are expected to grow at a high CAGR during the forecast period. Increasing focus on proteomics research and rising government support for research activities are some of the major factors expected to propel the market growth during the forecast period.

The global cell-free expression system market is expected to generate revenue amounting to USD 211.56 million in 2020, and is projected to reach to USD 302.65 million by 2026, growing at a CAGR 6.15% over the forecast period. Cell-free expression is used in many applications such as high throughput screen for truncated proteins, making proteins that are toxic to expression hosts in vivo, expression of proteins with amino acids, and incorporation of post-translational modifications, among others.

On the basis of product & services, the global protein expression market is segmented into reagents, expression vectors, competent cells, instruments, and services. The reagents segment is expected to hold the largest market share during the forecast period. Reagent products are widely used by research institutes, biotechnology, and pharmaceutical companies for development, and manufacturing of insulin, and human growth hormone. The service segment is expected to grow at a significant CAGR during the forecast period. The growing demand for customized protein expressions are driving the market growth for service segment.

On the basis of application, the market is segmented into therapeutic applications, industrial applications, and research applications. The therapeutic application segment is expected to hold the largest market share and is also expected to grow at a high CAGR in the global protein expression market during the forecast period.  Protein expression products provide high accuracy, efficiency, and quality in biologics production. The therapeutic proteins include insulin, monoclonal antibodies, growth factors, hormones, blood factors, anticoagulants, enzymes, interleukins, and interferons among others. These proteins are widely used for treatment of chronic diseases.

On the basis of end use, the global protein expression market is segmented into pharmaceutical and biotechnology companies, academic research institutes, and contract research organizations among others. The pharmaceutical and biotechnology segment is expected to hold the largest market share during the forecast period. Rising demand for therapeutic proteins such as insulin, growth hormone, and vaccines along with increased investment in new drug designing and development are some of the major factors expected to drive the market growth for pharmaceutical & biotechnology segment during the forecast period.

Protein Expression Market

Global Protein Expression Market – Regional Analysis

On the basis of region, the market of protein expression is segmented into North America, Europe, Asia Pacific, Central & South America, and Middle East & Africa. The North America region is expected to dominate the market during the forecast period. The presence of large biopharmaceuticals, biotechnology, and pharmaceutical companies such as Pfizer Inc., Merck KGaA, F. Hoffmann-La Roche Ltd, and Amgen Inc. among others in the region is driving the market growth. Asia Pacific region is expected to grow at the highest CAGR during the forecast period. Rising penetration of contract research organizations and developing healthcare infrastructure in developing countries including India and China are propelling the market growth in the region.

Use Cases:

In March 2020, Thermo Fisher Scientific Inc. acquired German based biotechnology company, Qiagen. This acquisition will help Thermo Fisher Scientific to enhance its precision medicine portfolio through molecular diagnostics and improved life sciences solutions.

In January 2020, Merck planned for the construction of a new biotech development facility in Switzerland. The company will be investing approximately EURO 250 million for construction of its new facility.

In 2018, Thermo Fisher Scientific Inc. launched the Gibco ExpiSf System, which is the first-ever chemically defined insect protein expression system.

Check the Press Release on Global Protein Expression Market Report

Protein Expression Market: By System Type

  1. Introduction   
    1. Protein Expression Market, By System Type, 2018-2026 (USD Million)
  2. Biodegradable Protein Expression     
    1. Biodegradable Protein Expression: Protein Expression Market, 2018-2026 (USD Million        
  3. Mammalian cell systems Protein Expression  
    1. Mammalian cell systems Protein Expression: Protein Expression Market, 2018-2026 (USD Million)
  4. Insect cell systems    
    1. Insect cell systems: Protein Expression Market, 2018-2026 (USD Million)
  5. Yeast Expression systems     
    1. Yeast Expression systems: Protein Expression Market, 2018-2026 (USD Million)
  6. Cell-Free Expression Systems
    1. Cell-Free Expression Systems: Protein Expression Market, 2018-2026 (USD Million)
  7. Algal Expression Systems      
    1. Algal Expression Systems: Protein Expression Market, 2018-2026 (USD Million)

Protein Expression Market: By Product & Services

  1. Introduction   
    1. Protein Expression Market, By Product & Services Type, 2018-2026 (USD Million)     
  2. Reagents       
    1. Reagents: Protein Expression Market, 2018-2026 (USD Million)         
  3. Expression vectors    
    1. Expression vectors: Protein Expression Market, 2018-2026 (USD Million)
  4. Competent cells        
    1. Competent cells: Protein Expression Market, 2018-2026 (USD Million)
  5. Instruments   
    1. Instruments: Protein Expression Market, 2018-2026 (USD Million)
  6. Services        
    1. Services: Protein Expression Market, 2018-2026 (USD Million)

Protein Expression Market: By Application

  1. Introduction   
    1. Protein Expression Market, By Application, 2018-2026 (USD Million)  
  2. Therapeutic   
    1. Therapeutic: Protein Expression Market, 2018-2026 (USD Million)     
  3. Industrial Application 
    1. Industrial Application: Protein Expression Market, 2018-2026 (USD Million)
  4. Research Application
    1. Research Application: Protein Expression Market, 2018-2026 (USD Million)

Protein Expression Market: By End Use

  1. Introduction   
    1. Protein Expression Market, By End Use, 2018-2026 (USD Million)      
  2. Pharmaceutical and biotechnological companies      
    1. Pharmaceutical and biotechnological companies: Protein Expression Market, 2018-2026 (USD Million)    
  3. Academic research    
    1. Academic research: Protein Expression Market, 2018-2026 (USD Million)
  4. Contract research organizations        
    1. Contract research organizations: Protein Expression Market, 2018-2026 (USD Million)
  5. Others
    1. Others: Protein Expression Market, 2018-2026 (USD Million) 

Protein Expression Market: By Region

  1. Introduction    
    1. Global Protein Expression Market, Regional Analysis, 2018-2026 (USD Million)         
  2. North America
    1. North America Protein Expression Market, Regional Analysis, 2018-2026 (USD Million)         
      1. By System Type
        1. North America Protein Expression Market, By System Type, 2018-2026 (USD Million)             
      2. By Product & Services   
        1. North America Protein Expression Market, By Product & Services, 2018-2026 (USD Million)              
      3. By Application  
        1. North America Protein Expression Market, By Application, 2018-2026 (USD Million)             
      4. By End Use        
        1. North America Protein Expression Market, By End Use, 2018-2026 (USD Million)
      5. By Country         
        1. U.S        
          1. By System Type
            1. U.S. Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. U.S. Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. U.S. Protein Expression Market, By Application, 2018-2026 (USD Million)
          4. By End Use        
            1. U.S. Protein Expression Market, By End Use, 2018-2026 (USD Million)      
        2. Canada.               
          1. By System Type
            1. Canada Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. Canada Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. Canada Protein Expression Market, By Application, 2018-2026 (USD Million)       
          4. By End Use        
            1. Canada Protein Expression Market, By End Use, 2018-2026 (USD Million)       
        3. Mexico
          1. By System Type
            1. Mexico Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. Mexico Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. Mexico Protein Expression Market, By Application, 2018-2026 (USD Million)       
          4. By End Use        
            1. Mexico Protein Expression Market, By End Use, 2018-2026 (USD Million)
  3. Europe
    1. Europe Protein Expression Market, Regional Analysis, 2018-2026 (USD Million)        
      1. By System Type
        1. Europe Protein Expression Market, By System Type, 2018-2026 (USD Million)      
      2. By Product & Services   
        1. Europe Protein Expression Market, By Product & Services, 2018-2026 (USD Million)             
      3. By Application  
        1. Europe Protein Expression Market, By Application, 2018-2026 (USD Million)         
      4. By End Use        
        1. Europe Protein Expression Market, By End Use, 2018-2026 (USD Million)
      5. By Country         
        1. Germany            
          1. By System Type
            1. Germany Protein Expression Market, By System Type, 2018-2026 (USD Million)        
          2. By Product & Services   
            1. Germany Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. Germany Protein Expression Market, By Vertcal, 2018-2026 (USD Million)       
          4. By End Use        
            1. Germany Protein Expression Market, By End Use, 2018-2026 (USD Million)       
        2. UK         
          1. By System Type
            1. UK Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. UK Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. UK Protein Expression Market, By Application, 2018-2026 (USD Million) 
          4. By End Use        
            1. UK Protein Expression Market, By End Use, 2018-2026 (USD Million)        
        3. France 
          1. By System Type
            1. France Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. France Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. France Protein Expression Market, By Application, 2018-2026 (USD Million)       
          4. By End Use        
            1. France Protein Expression Market, By End Use, 2018-2026 (USD Million)
        4. Italy      
          1. By System Type
            1. Italy Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. Italy Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. Italy Protein Expression Market, By Application, 2018-2026 (USD Million)       
          4. By End Use        
            1. Italy Protein Expression Market, By End Use, 2018-2026 (USD Million)     
        5. Spain    
          1. By System Type
            1. Spain Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. Spain Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. Spain Protein Expression Market, By Application, 2018-2026 (USD Million)       
          4. By End Use        
            1. Spain Protein Expression Market, By End Use, 2018-2026 (USD Million)           
        6. Belgium               
          1. By System Type
            1. Belgium Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. Belgium Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. Belgium Protein Expression Market, By Application, 2018-2026 (USD Million)       
          4. By End Use        
            1. Belgium Protein Expression Market, By End Use, 2018-2026 (USD Million)       
        7. Rest Of Europe 
          1. By System Type
            1. Rest Of Europe Protein Expression Market, By System Type, 2018-2026 (USD Million)        
          2. By Product & Services   
            1. Rest Of Europe Protein Expression Market, By Product & Services, 2018-2026 (USD Million)             
          3. By Application  
            1. Rest Of Europe Protein Expression Market, By Application, 2018-2026 (USD Million)        
          4. By End Use        
            1. Rest Of Europe Protein Expression Market, By End Use, 2018-2026 (USD Million)        
  4. Asia Pacific       
    1. Asia Pacific Protein Expression Market, Regional Analysis, 2018-2026 (USD Million)
      1. By System Type
        1. Asia Pacific Protein Expression Market, By System Type, 2018-2026 (USD Million)             
      2. By Product & Services   
        1. Asia Pacific Protein Expression Market, By Product & Services, 2018-2026 (USD Million)              
      3. By Application  
        1. Asia Pacific Protein Expression Market, By Application, 2018-2026 (USD Million) 
      4. By End Use        
        1. Asia Pacific Protein Expression Market, By End Use, 2018-2026 (USD Million)       
      5. By Country         
        1. China    
          1. By System Type
            1. China Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. China Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. China Protein Expression Market, By Application, 2018-2026 (USD Million)       
          4. By End Use        
            1. China Protein Expression Market, By End Use, 2018-2026 (USD Million)  
        2. Japan   
          1. By System Type
            1. Japan Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. Japan Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. Japan Protein Expression Market, By Application, 2018-2026 (USD Million)       
          4. By End Use        
            1. Japan Protein Expression Market, By End Use, 2018-2026 (USD Million)  
        3. India     
          1. By System Type
            1. India Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. India Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. India Protein Expression Market, By Application, 2018-2026 (USD Million)       
          4. By End Use        
            1. India Protein Expression Market, By End Use, 2018-2026 (USD Million)    
        4. South Korea      
          1. By System Type
            1. South Korea Protein Expression Market, By System Type, 2018-2026 (USD Million)        
          2. By Product & Services   
            1. South Korea Protein Expression Market, By Product & Services, 2018-2026 (USD Million)             
          3. By Application  
            1. South Korea Protein Expression Market, By Application, 2018-2026 (USD Million)        
          4. By End Use        
            1. South Korea Protein Expression Market, By End Use, 2018-2026 (USD Million)
        5. Rest Of Apac     
          1. By System Type
            1. Rest Of Apac, Protein Expression Market, By System Type, 2018-2026 (USD Million)        
          2. By Product & Services   
            1. Rest Of Apac Protein Expression Market, By Product & Services, 2018-2026 (USD Million)             
          3. By Application  
            1. Rest Of Apac Protein Expression Market, By Application, 2018-2026 (USD Million)        
          4. By End Use        
            1. Rest Of Apac Protein Expression Market, By End Use, 2018-2026 (USD Million)       
  5. Central & South America            
    1. Central & South America Protein Expression Market, Regional Analysis, 2018-2026 (USD Million)     
      1. By System Type
        1. Central & South America Protein Expression Market, By System Type, 2018-2026 (USD Million)              
      2. By Product & Services   
        1. Central & South America Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
      3. By Application  
        1. Central & South America Protein Expression Market, By Application, 2018-2026 (USD Million)              
      4. By End Use        
        1. Central & South America Protein Expression Market, By End Use, 2018-2026 (USD Million)              
      5. By Country         
        1. Brazil    
          1. By System Type
            1. Brazil Protein Expression Market, By System Type, 2018-2026 (USD Million)       
          2. By Product & Services   
            1. Brazil Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
          3. By Application  
            1. Brazil Protein Expression Market, By Application, 2018-2026 (USD Million)       
          4. By End Use        
            1. Brazil Protein Expression Market, By End Use, 2018-2026 (USD Million)   
    2. Middle East & Africa     
      1. Middle East & Africa Protein Expression Market, Regional Analysis, 2018-2026 (USD Million)             
        1. By System Type
          1. Middle East & Africa Protein Expression Market, By System Type, 2018-2026 (USD Million)              
        2. By Product & Services   
          1. Middle East & Africa Protein Expression Market, By Product & Services, 2018-2026 (USD Million)   
        3. By Application  
          1. Middle East & Africa Protein Expression Market, By Application, 2018-2026 (USD Million)              
        4. By End Use        
          1. Middle East & Africa Protein Expression Market, By End Use, 2018-2026 (USD Million)             
        5. By Country         
          1. Saudi Arabia      
            1. By System Type
              1. Saudi Arabia Protein Expression Market, By System Type, 2018-2026 (USD Million)        
            2. By Product & Services   
              1. Saudi Arabia Protein Expression Market, By Product & Services, 2018-2026 (USD Million)             
            3. By Application  
              1. Saudi Arabia Protein Expression Market, By Application, 2018-2026 (USD Million)        
            4. By End Use        
              1. Saudi Arabia Protein Expression Market, By End Use, 2018-2026 (USD Million)       
          2. UAE      
            1. By System Type
              1. UAE Protein Expression Market, By System Type, 2018-2026 (USD Million)       
            2. By Product & Services   
              1. UAE Protein Expression Market, By Product & Services, 2018-2026 (USD Million)        
            3. By Application  
              1. UAE Protein Expression Market, By Application, 2018-2026 (USD Million)       
            4. By End Use        
              1. UAE Protein Expression Market, By End Use, 2018-2026 (USD Million)

The global Protein Expression Market has been studied from the year 2017 till 2026. However, the CAGR provided in the report is from the year 2018 to 2026. The research methodology involved three stages: Desk research, Primary research, and Analysis & Output from the entire research process.

Protein Expression Market

The desk research involved a robust background study which meant referring to paid and unpaid databases to understand the market dynamics; mapping contracts from press releases; identifying the key players in the market, studying their product portfolio, competition level, annual reports/SEC filings & investor presentations; and learning the demand and supply side analysis for the Protein Expression Market.

Protein Expression Market

The primary research activity included telephonic conversations with more than 50 tier 1 industry consultants, distributors, and end-use product manufacturers.

Protein Expression Market

Finally, based on the above thorough research process, an in-depth analysis was carried out considering the following aspects: market attractiveness, current & future market trends, market share analysis, SWOT analysis of the companies and customer analytics.

Protein Expression Market

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